Three New Sesquiterpenoids and One New Sesquiterpenoid Derivative from Chinese Eaglewood.

نویسندگان

  • Huan Zhao
  • Qinghua Peng
  • Zhuzhen Han
  • Li Yang
  • Zhengtao Wang
چکیده

Three new sesquiterpenoids (1-3) and one new sesquiterpenoid derivative (4), along with three known sesquiterpenoids (5-7), were isolated from the 95% ethanolic extract of Chinese eaglewood [Aquilaria sinensis (Lour.) Gilg]. The structures of these compounds were elucidated through extensive analysis of spectroscopic data including IR, NMR, HRESIMS, and X-ray diffraction experiments. In addition, the above new compounds were detected for their bioactivities against LPS-induced NO production in RAW 264.7 cells. Among them, compound 2 exhibited obvious anti-inflammatory activity with an IC50 value of 8.1 μM.

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عنوان ژورنال:
  • Molecules

دوره 21 3  شماره 

صفحات  -

تاریخ انتشار 2016